SCHEMBL2295334

SCHEMBL2295334

Cc1ccc(N(S(=O)(=O)CC(F)(F)F)S(=O)(=O)CC(F)(F)F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
MAPT P10636 2/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
CA5A P35218 1/20 0.39
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HCRTR2 O43614 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
TSHR P16473 1/20 0.35
GRM2 Q14416 2/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16907556 0.75 MMP2 (0.37) RORCCA1CA2CA9MAPT
SCHEMBL2199940 0.75 CA9 (0.47) RORCCA1CA2CA9MAPT
SCHEMBL2295332 0.73 CA9 (0.42) RORCCA1CA2CA9MAPT
SCHEMBL6191256 0.71 GRM2 (0.39) RORCALDH1A1MEN1KMT2AGRM2
SCHEMBL26310493 0.71 MAPT (0.47) CA1CA2CA9MAPTMCOLN3
SCHEMBL14872862 0.70 CA2 (0.50) CA1CA2CA9CA5AALDH1A1
SCHEMBL10483623 0.69 HSP90AA1 (0.51) RORCCA9ALDH1A1NPSR1L3MBTL1
SCHEMBL12994623 0.69 MAPT (0.48) CA1CA2CA9MAPTMCOLN3
SCHEMBL28298151 0.68 MAPT (0.41) CA9MAPTMCOLN3ALDH1A1MEN1
SCHEMBL11598690 0.67 MAPT (0.47) CA1CA2CA9MAPTMCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2345675-A1 A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE Petrochina Company Limited (CN) 2011-07-20 EP claimed