Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199940 | 0.81 | CA9 (0.47) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL2295334 | 0.73 | RORC (0.40) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL26310493 | 0.70 | MAPT (0.47) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL12994623 | 0.68 | MAPT (0.48) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL16907556 | 0.67 | MMP2 (0.37) | CA9CA1CA2CA5AALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL6423653 | 0.67 | ALDH1A1 (0.58) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL28298151 | 0.67 | MAPT (0.41) | CA9ALDH1A1TSHRMAPTMCOLN3 | |
| SCHEMBL11598690 | 0.66 | MAPT (0.47) | CA9CA1CA2CA5AALDH1A1 | |
| SCHEMBL1087579 | 0.65 | MAPT (0.39) | CA9ALDH1A1TSHRMAPTMCOLN3 | |
| SCHEMBL28384073 | 0.63 | CA2 (0.35) | CA9CA1CA2CA5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345675-A1 | A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE | Petrochina Company Limited (CN) | 2011-07-20 | — | — | EP | claimed |