Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ENO1 | P06733 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27935423 | 0.92 | HPGD (0.34) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27950765 | 0.92 | HPGD (0.34) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28824422 | 0.86 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27789516 | 0.83 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27941707 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTENO1 | |
| SCHEMBL27890346 | 0.83 | — | — | |
| SCHEMBL27643661 | 0.81 | HPGD (0.36) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL18166955 | 0.80 | CHRM2 (0.33) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27698740 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28787824 | 0.79 | LMNA (0.33) | MEN1KMT2AALDH1A1MAPTENO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001271-B | Hydroxyamidine derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2019-05-10 | — | — | CN | disclosed |