Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28125892 | 0.92 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1BCHELMNAGAA | |
| SCHEMBL27789516 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MAPK1BCHELMNAKMT2A | |
| SCHEMBL28298317 | 0.86 | MEN1 (0.38) | ALDH1A1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL28172922 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPK1BCHELMNAGAA | |
| SCHEMBL28125502 | 0.83 | ATM (0.35) | GAASMN1; SMN2 | |
| SCHEMBL27941707 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1BCHELMNAGAA | |
| SCHEMBL27915375 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL26094335 | 0.81 | ENO1 (0.32) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL26628945 | 0.81 | ENO1 (0.32) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL26094973 | 0.81 | ENO1 (0.32) | ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163738-A | MK2 inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-16 | — | — | CN | disclosed |