Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807037 | 0.82 | MAOB (0.60) | MAOBXDHGAAMAPTMAOA | |
| SCHEMBL2700393 | 0.82 | MAOB (0.56) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL28051198 | 0.82 | MAOB (0.47) | MAOBXDHFNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL4488053 | 0.81 | MAOB (0.55) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL4452726 | 0.78 | NPC1 (0.52) | MAOBSQORXDHFNTAFNTB | |
| SCHEMBL25330736 | 0.75 | KDM1A (0.47) | MAOBEGFRERBB2AS3MTNSD2 | |
| SCHEMBL4056945 | 0.74 | MAOB (0.51) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL11133548 | 0.74 | MAOB (0.53) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL5741190 | 0.74 | NPC1 (0.62) | MAOBAS3MTSQORMAPTRAB9A | |
| SCHEMBL448079 | 0.74 | MAOB (0.57) | MAOBXDHFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |