SCHEMBL4452726

SCHEMBL4452726

N#Cc1cccc(OCc2ccccc2)c1C#N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
SGMS2 Q8NHU3 2/20 0.52
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MAOB P27338 2/20 0.51
MRGPRX4 Q96LA9 1/20 0.49
VEGFA P15692 1/20 0.46
GRM2 Q14416 1/20 0.46
HTR1A P08908 1/20 0.45
DRD2 P14416 1/20 0.45
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SQOR Q9Y6N5 1/20 0.44
XDH P47989 1/20 0.44
LIPE Q05469 1/20 0.44
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5741190 0.90 NPC1 (0.62) NPC1RAB9ASGMS2MAPTMAPK1
SCHEMBL448079 0.86 MAOB (0.57) SGMS2MAPTMAPK1TDP1L3MBTL1
SCHEMBL28598683 0.86 NPC1 (0.52) NPC1RAB9ASGMS2MAPTMAPK1
SCHEMBL25079152 0.83 SGMS2 (0.52) SGMS2MAPTMAPK1TDP1L3MBTL1
SCHEMBL30257271 0.83 SGMS2 (0.52) SGMS2MAPTMAPK1TDP1L3MBTL1
SCHEMBL15602827 0.83 SGMS2 (0.52) SGMS2MAPTMAPK1TDP1L3MBTL1
SCHEMBL3922233 0.82 SGMS2 (0.51) SGMS2MAPTMAPK1TDP1L3MBTL1
SCHEMBL621853 0.82 NPC1 (0.51) NPC1RAB9ASGMS2MAPTMAPK1
SCHEMBL2657882 0.82 SGMS2 (0.51) SGMS2MAPTMAPK1TDP1L3MBTL1
SCHEMBL8874717 0.82 SQOR (0.57) NPC1RAB9ASGMS2MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582230-B2 Contains tetrahydroxy- or tetraalkoxy-substituted phthalocyanine CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-01 US disclosed
CN-100360535-C Liquid crystal display and colour filter with improved transparency for green light CIBA SC HOLDING AG (CH) 2008-01-09 CN disclosed
EP-1534714-B1 LIQUID CRYSTAL DISPLAY AND COLOUR FILTER WITH IMPROVED TRANSPARENCY FOR GREEN LIGHT CIBA SC HOLDING AG (CH) 2007-05-16 EP disclosed
US-20060060829-A1 Liquid crystal display and colour filter with improved transparency for green light CIBA SPECIALTY CHEMICALS CORP. 2006-03-23 US disclosed
CN-1675216-A Liquid crystal display and colour filter with improved transparency for green light CIBA SC HOLDING AG (CH) 2005-09-28 CN disclosed
EP-1534714-A2 LIQUID CRYSTAL DISPLAY AND COLOUR FILTER WITH IMPROVED TRANSPARENCY FOR GREEN LIGHT Ciba SC Holding AG (CH) 2005-06-01 EP disclosed
WO-2004018477-A2 LIQUID CRYSTAL DISPLAY AND COLOUR FILTER WITH IMPROVED TRANSPARENCY FOR GREEN LIGHT CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) 2004-03-04 WO disclosed