Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423700 | 0.88 | KMO (0.56) | KMOCA12CA1CA2CA6 | |
| SCHEMBL2020761 | 0.87 | KMO (0.60) | KMOCA12CA1CA2CA6 | |
| SCHEMBL16426263 | 0.86 | BRD4 (0.55) | CNR1CNR2 | |
| SCHEMBL6564927 | 0.83 | CA12 (0.53) | KMOCA12CA1CA2CA6 | |
| SCHEMBL4584346 | 0.82 | KMO (0.58) | KMOCA12CA1CA2CA6 | |
| SCHEMBL5428822 | 0.82 | RAB9A (0.51) | KMORXRARXRBAKR1C3AKR1C2 | |
| SCHEMBL31658247 | 0.82 | TTR (0.53) | KMORXRARXRBAKR1C3AKR1C2 | |
| SCHEMBL11227165 | 0.81 | KMO (0.72) | KMOCA12CA1CA2CA6 | |
| SCHEMBL15398033 | 0.79 | KMO (0.50) | KMOCA12CA1CA2CA6 | |
| SCHEMBL18788839 | 0.78 | KMO (0.68) | KMOCA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003074-B | Biphenyl carboxylic acid compound and preparation method and application thereof | 四川大学华西医院 | 2019-07-05 | — | — | CN | disclosed |