SCHEMBL5428822

SCHEMBL5428822

COc1cc(C)c(-c2cccc(C(=O)O)c2)c(C)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
FFAR1 O14842 4/20 0.51
LMNA P02545 2/20 0.50
KMO O15229 1/20 0.50
GAA P10253 1/20 0.50
ERN1 O75460 1/20 0.49
RXRA P19793 2/20 0.49
RXRB P28702 1/20 0.49
STIM1 Q13586 1/20 0.48
ORAI1 Q96D31 1/20 0.48
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48
MRGPRX4 Q96LA9 2/20 0.48
MITF O75030 1/20 0.48
TP53 P04637 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5433882 0.86 FFAR1 (0.47) SMN1; SMN2MEN1KMT2AFFAR1LMNA
SCHEMBL12581548 0.84 LMNA (0.61) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL5428883 0.84 MEN1 (0.51) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL5423700 0.83 KMO (0.56) LMNAKMOGAARXRARXRB
SCHEMBL2020761 0.83 KMO (0.60) RAB9ANPC1SMN1; SMN2FFAR1LMNA
SCHEMBL4179829 0.82 RXRA (0.67) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL28298835 0.82 KMO (0.55) LMNAKMOGAAERN1RXRA
SCHEMBL4254012 0.80 STIM1 (0.62) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL5523606 0.79 ERN1 (0.59) RAB9ANPC1LMNAKMOGAA
SCHEMBL3639698 0.79 SMN1; SMN2 (0.74) RAB9ANPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070135497-A1 Biphenyl derivative or its salt, and pesticide containing it as an active ingredient ISHIHARA SANGYO KAISHA LTD. (JP) 2007-06-14 US disclosed
EP-1681924-A1 BIPHENYL DERIVATIVE OR ITS SALT, AND PESTICIDE CONTAINING IT AS AN ACTIVE INGREDIENT ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-26 EP disclosed
WO-2005044007-A1 BIPHENYL DERIVATIVE OR ITS SALT, AND PESTICIDE CONTAINING IT AS AN ACTIVE INGREDIENT ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135497-A1 Biphenyl derivative or its salt, and pesticide containing it as an active ingredient DDT, HCN1, HCN2 RAB9A 1792/4885NPC1 2917/4885SMN1; SMN2 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.