SCHEMBL28298919

SCHEMBL28298919

CCCN(CCC)C(=O)Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
TP53 P04637 1/20 0.52
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SRD5A1 P18405 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 2/20 0.45
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PKM P14618 1/20 0.45
ACHE P22303 1/20 0.44
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18082510 0.89 MEN1 (0.47) KMT2AMEN1TP53ATMTDP1
SCHEMBL6754891 0.86 MEN1 (0.51) KMT2AMEN1ATMTDP1L3MBTL1
SCHEMBL5623546 0.85 MEN1 (0.81) KMT2AMEN1TP53ATMTDP1
SCHEMBL3475215 0.84 ACHE (0.61) KMT2AMEN1ATMTDP1L3MBTL1
SCHEMBL22450141 0.83 MEN1 (0.61) KMT2AMEN1ATMTDP1L3MBTL1
SCHEMBL28165222 0.82 L3MBTL1 (0.49) KMT2AMEN1TP53ATMTDP1
SCHEMBL11187935 0.82 L3MBTL1 (0.49) KMT2AMEN1TP53ATMTDP1
SCHEMBL11307504 0.81 KMT2A (0.69) KMT2AMEN1ATMTDP1L3MBTL1
SCHEMBL3991075 0.81 TDP1 (0.52) KMT2AMEN1ATMTDP1L3MBTL1
SCHEMBL9373248 0.81 MEN1 (0.46) KMT2AMEN1RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106133004-B Catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2019-05-07 CN disclosed
CN-107278209-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2017-10-20 CN disclosed