Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31504001 | 0.88 | LMNA (0.50) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL3483514 | 0.88 | LMNA (0.50) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL6754891 | 0.87 | MEN1 (0.51) | MEN1KMT2ALMNAMAPTATM | |
| SCHEMBL5623546 | 0.86 | MEN1 (0.81) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL22622046 | 0.85 | LMNA (0.48) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL11307504 | 0.83 | KMT2A (0.69) | MEN1KMT2ALMNASMN1; SMN2HSD17B10 | |
| SCHEMBL28298919 | 0.83 | KMT2A (0.58) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL4854943 | 0.82 | ACHE (0.52) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9373248 | 0.82 | MEN1 (0.46) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL9160789 | 0.81 | MEN1 (0.45) | MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712140-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | California Institute of Technology (US) | 2020-09-23 | — | — | EP | disclosed |