Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785688 | 0.84 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1GLAPDK2MAPT | |
| SCHEMBL7931698 | 0.81 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1GLAMAPTGAA | |
| SCHEMBL29951150 | 0.80 | ENPP2 (0.46) | L3MBTL1ALDH1A1GLAPDK2MAPT | |
| SCHEMBL14120757 | 0.80 | ENPP2 (0.46) | L3MBTL1ALDH1A1GLAPDK2MAPT | |
| SCHEMBL10762652 | 0.77 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1GLAMAPTATM | |
| SCHEMBL1066091 | 0.76 | TSHR (0.45) | L3MBTL1ALDH1A1GLAPDK2MAPT | |
| SCHEMBL29544564 | 0.75 | TSHR (0.43) | L3MBTL1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6680350 | 0.75 | TSHR (0.43) | L3MBTL1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1547751 | 0.75 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTATMRAB9A | |
| Methyl Alcohol SCHEMBL11789519 | 0.74 | TSHR (0.43) | L3MBTL1ALDH1A1GLAPDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-A | Aryl-linking compound as immunomodulator | 百时美施贵宝公司 | 2019-06-07 | — | — | CN | disclosed |