SCHEMBL28298962

SCHEMBL28298962

Cc1cc([N+](=O)[O-])ccc1O.[NaH]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
TSHR P16473 5/20 0.64
TDP1 Q9NUW8 2/20 0.64
GPR35 Q9HC97 3/20 0.60
CYP3A4 P08684 2/20 0.60
TP53 P04637 1/20 0.60
HPGD P15428 1/20 0.60
MAPK1 P28482 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
GAA P10253 2/20 0.58
THRB P10828 1/20 0.58
ERN1 O75460 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.53
POLB P06746 1/20 0.49
ACHE P22303 2/20 0.48
HSD17B10 Q99714 1/20 0.48
HSP90AA1 P07900 1/20 0.47
ALOX15 P16050 1/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61129 0.98 ALDH1A1 (0.67) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL28782982 0.88 PDE10A (0.63) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL29431205 0.84 ALDH1A1 (0.56) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL16701937 0.83 HSD17B1 (0.51) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL27661134 0.82 TSHR (0.54) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL61902 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1GPR35CYP3A4
4-Nitrocatechol SCHEMBL28290085 0.81 ALDH1A1 (0.67) ALDH1A1TSHRTDP1GPR35TP53
Ammonia Solution, Strong SCHEMBL9388499 0.80 ALDH1A1 (0.64) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL12932222 0.79 TDP1 (0.48) ALDH1A1TSHRTDP1GPR35CYP3A4
SCHEMBL16076897 0.79 TSHR (0.56) ALDH1A1TSHRTDP1THRBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109704897-B Wastewater recycling method based on dimethyl sulfate 安徽节源环保科技有限公司 2020-07-03 CN disclosed
CN-109704897-A A kind of waste water recycling method based on dimethyl suflfate 安徽节源环保科技有限公司 2019-05-03 CN disclosed