Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | TSHR | P16473 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9388499 | 0.98 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| Methacrylic Acid SCHEMBL29724198 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL61129 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL28298962 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL11028069 | 0.80 | GPR35 (0.69) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| SCHEMBL384312 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| 4-Nitrocatechol SCHEMBL11765698 | 0.80 | TSHR (0.69) | ALDH1A1TSHRTDP1GPR35SMN1; SMN2 | |
| SCHEMBL29511002 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1GPR35CYP3A4 | |
| 4-Nitrocatechol SCHEMBL156909 | 0.80 | TSHR (0.69) | ALDH1A1TSHRTDP1GPR35SMN1; SMN2 | |
| 4-Nitrocatechol SCHEMBL1608536 | 0.80 | TSHR (0.69) | ALDH1A1TSHRTDP1GPR35SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899194-B | Bicyclic heteroaryl BRAF negative allosteric modulator, and preparation method and application thereof | 浙江省人民医院 | 2025-06-24 | — | — | CN | claimed |
| CN-119899194-A | Bicyclic heteroaryl BRAF negative allosteric modulator, and preparation method and application thereof | 浙江省人民医院 | 2025-04-29 | — | — | CN | claimed |
| CN-111662192-A | Synthesis process of 4-amino-6-hydroxy benzyl bromide | 湖北仙盛科技股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-105837452-B | 2- methyl-5-nitro phenol production process | 田志高 | 2019-01-29 | — | — | CN | claimed |
| CN-105837452-A | Production method of 2-methyl-5-nitrophenol | 田志高 | 2016-08-10 | — | — | CN | claimed |
| CN-105218376-A | A kind of synthetic method of 2-methyl-5-nitro phenol | DING YUQIN | 2016-01-06 | — | — | CN | claimed |
| EP-1437749-B1 | ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR | RUBYCON CORP (JP) | 2013-07-17 | — | — | EP | claimed |
| US-20100258033-A1 | WOOD ADHESIVE AND METHOD OF PREPARING THEREOF | YANG GUANG | 2010-10-14 | — | — | US | claimed |
| EP-2236578-A1 | A NEW LUMBER ADHESIVE AND THE PREPARATION THEREOF | Yang, Guang (CN) | 2010-10-06 | — | — | EP | claimed |
| US-7539006-B2 | Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor | RUBYCON CORPORATION (JP) | 2009-05-26 | — | — | US | claimed |
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-22 | — | — | US | claimed |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-05-08 | — | — | US | claimed |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-01 | — | — | US | claimed |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-02-13 | — | — | US | claimed |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| EP-1115693-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| EP-0999823-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2000-05-17 | — | — | EP | claimed |
| WO-2000018721-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-1999020235-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 1999-04-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | ALDH1A1 2277/4885TSHR 3307/4885TDP1 1720/4885 |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, LCAT, MTTP | ALDH1A1 2079/4885TSHR 4233/4885TDP1 1793/4885 |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | ALDH1A1 2277/4885TSHR 3307/4885TDP1 1720/4885 |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | ALDH1A1 2277/4885TSHR 3307/4885TDP1 1720/4885 |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, PCTP | ALDH1A1 2611/4885TSHR 2481/4885TDP1 1817/4885 |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | ALDH1A1 2588/4885TSHR 4329/4885TDP1 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.