Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926472 | 0.82 | TDP1 (0.48) | TDP1METHSP90AA1ALDH1A1GAA | |
| SCHEMBL31435498 | 0.80 | TSHR (0.53) | KMT2AMEN1TDP1METHSP90AA1 | |
| SCHEMBL3240302 | 0.79 | GAA (0.42) | TDP1METHSP90AA1ALDH1A1GAA | |
| SCHEMBL30123312 | 0.79 | GAA (0.42) | TDP1METHSP90AA1ALDH1A1GAA | |
| SCHEMBL30760162 | 0.72 | TSHR (0.57) | KMT2AALDH1A1BCHE | |
| SCHEMBL28299076 | 0.72 | MGLL (0.49) | ALDH1A1GAASMN1; SMN2MGLL | |
| SCHEMBL11223006 | 0.70 | TDP1 (0.53) | KMT2AMEN1TDP1HSP90AA1ALDH1A1 | |
| SCHEMBL27421511 | 0.70 | KMT2A (0.59) | KMT2AMEN1TDP1ALDH1A1ALOX5 | |
| SCHEMBL3165711 | 0.70 | KMT2A (0.50) | KMT2ATDP1HSP90AA1ALDH1A1GAA | |
| SCHEMBL4417523 | 0.69 | GAA (0.44) | KMT2AMEN1TDP1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232584-B | As 6 inhibitor of histone deacetylase new compound and include its pharmaceutical composition | 株式会社钟根堂 | 2019-06-28 | — | — | CN | disclosed |