Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923128 | 0.85 | GAA (0.42) | GAATDP1HSP90AA1ALDH1A1GPR35 | |
| SCHEMBL27792905 | 0.84 | BCL9 (0.41) | GAATDP1HSP90AA1ALDH1A1MEN1 | |
| SCHEMBL4425276 | 0.77 | HTR2C (0.42) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL16493596 | 0.76 | NOTUM (0.37) | TDP1ALDH1A1MEN1KMT2ACCR2 | |
| SCHEMBL27632906 | 0.75 | CREBBP (0.44) | GAATDP1ALDH1A1GPR35MEN1 | |
| SCHEMBL27695721 | 0.75 | TDP1 (0.41) | GAATDP1ALDH1A1GPR35MEN1 | |
| SCHEMBL7333463 | 0.75 | GAA (0.41) | GAATDP1ALDH1A1GPR35L3MBTL1 | |
| SCHEMBL11223006 | 0.73 | TDP1 (0.53) | GAATDP1HSP90AA1ALDH1A1GPR35 | |
| SCHEMBL2475315 | 0.73 | GAA (0.66) | GAATDP1ALDH1A1GPR35TSHR | |
| SCHEMBL3653655 | 0.73 | HSPB1 (0.45) | GAAALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |