Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256730 | 0.80 | UCHL1 (0.53) | NPC1RAB9AALDH1A1 | |
| SCHEMBL2845554 | 0.80 | NPC1 (0.58) | ALOX5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17078868 | 0.76 | L3MBTL1 (0.60) | MEN1KMT2AFAAHTRPV1NPC1 | |
| SCHEMBL2850765 | 0.75 | NOTUM (0.43) | MEN1KMT2AAKR1C3AKR1C1NPC1 | |
| SCHEMBL14156442 | 0.74 | RAB9A (0.62) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28092728 | 0.74 | BCHE (0.41) | ALOX5MEN1KMT2AFAAHNPC1 | |
| SCHEMBL28294144 | 0.72 | HTR2A (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27666648 | 0.72 | MAPK1 (0.46) | MEN1KMT2AAKR1C3AKR1C1NPC1 | |
| SCHEMBL1853406 | 0.72 | MAPT (0.64) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27666646 | 0.70 | KMT2A (0.40) | MEN1KMT2AAKR1C3AKR1C1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232584-B | As 6 inhibitor of histone deacetylase new compound and include its pharmaceutical composition | 株式会社钟根堂 | 2019-06-28 | — | — | CN | disclosed |