Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299165 | 0.84 | CA2 (0.50) | CNR2KCNH3CA2CA1KDM4E | |
| SCHEMBL13605313 | 0.79 | KCNH3 (0.49) | CNR2KCNH3CSF1RKDRVNN1 | |
| SCHEMBL21259117 | 0.75 | KCNH3 (0.46) | CNR2KCNH3CSF1RKDRVNN1 | |
| SCHEMBL2482925 | 0.74 | CNR2 (0.48) | CNR2CA2CA1RORC | |
| SCHEMBL5793778 | 0.74 | KCNH3 (0.65) | CNR2KCNH3CSF1RKDRKDM4E | |
| SCHEMBL31480204 | 0.74 | AKR1C3 (0.51) | CNR2KCNH3VNN1KDM4ECRHR1 | |
| SCHEMBL27991145 | 0.73 | CA2 (0.52) | CA2CA1 | |
| SCHEMBL1238863 | 0.70 | MEN1 (0.57) | CA2CA1PTGS2 | |
| Sulfanilamide SCHEMBL1955933 | 0.70 | CA2 (0.47) | CNR2CA2CA1TDP1RORC | |
| SCHEMBL30078451 | 0.69 | RORC (0.48) | CNR2KCNH3CA2CA1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109966294-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109897038-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2019-06-18 | — | — | CN | disclosed |