Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454463 | 0.98 | CA2 (0.47) | CA2SMN1; SMN2HPGDALDH1A1HSD17B10 | |
| SCHEMBL7930478 | 0.95 | CA2 (0.50) | CA2SMN1; SMN2ALDH1A1HSD17B10STS | |
| SCHEMBL22666338 | 0.94 | CA2 (0.49) | CA2SMN1; SMN2ALDH1A1HSD17B10STS | |
| SCHEMBL17847695 | 0.90 | CA2 (0.46) | CA2STSDRD2DRD1DRD4 | |
| SCHEMBL8552231 | 0.90 | RARB (0.52) | CA2ALDH1A1HSD17B10STSFAAH | |
| SCHEMBL11409736 | 0.86 | PTGS2 (0.44) | CA2SMN1; SMN2DRD2DRD1DRD4 | |
| SCHEMBL14400508 | 0.83 | HTR1D (0.43) | CA2SMN1; SMN2HPGDALDH1A1HSD17B10 | |
| SCHEMBL14062440 | 0.82 | DRD2 (0.45) | CA2SMN1; SMN2ALDH1A1STSDRD2 | |
| SCHEMBL7932239 | 0.82 | CA2 (0.41) | CA2STSCA1HTR1AHTR1D | |
| SCHEMBL8622915 | 0.81 | ACACB (0.42) | CA2DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903316-B | Phosphonate compound and preparation method and application thereof | 中南大学 | 2021-03-02 | — | — | CN | claimed |
| CN-110903316-A | Phosphonate compound and preparation method and application thereof | 中南大学 | 2020-03-24 | — | — | CN | claimed |
| CN-110903316-B | Phosphonate compound and preparation method and application thereof | 中南大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-110903316-A | Phosphonate compound and preparation method and application thereof | 中南大学 | 2020-03-24 | — | — | CN | disclosed |
| CN-101735822-B | Preparation and use of low-temperature low-viscosity liquid crystal compositions | UNIV WUHAN POLYTECHNIC | 2015-04-29 | — | — | CN | disclosed |
| US-8981086-B2 | Phosphine-ligated palladium sulfonate palladacycles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20150045570-A1 | PHOSPHINE-LIGATED PALLADIUM SULFONATE PALLADACYCLES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-12 | — | — | US | disclosed |
| US-8889857-B2 | Phosphine-ligated palladium sulfonate palladacycles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8435387-B2 | Small-scale method and apparatus for separating mixtures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-07 | — | — | US | disclosed |
| CN-101735822-A | Preparation and use of low-temperature low-viscosity liquid crystal compositions | UNIV WUHAN POLYTECHNIC | 2010-06-16 | — | — | CN | disclosed |
| WO-2010056331-A2 | SMALL-SCALE METHOD AND APPRATUS FOR SEPARATING MIXTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100122899-A1 | SMALL-SCALE METHOD AND APPARATUS FOR SEPARATING MIXTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-20 | — | — | US | disclosed |
| EP-2077992-A2 | INDOLE ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | Brystol-Myers Squibb Company (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008048981-A2 | INDOLE ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-24 | — | — | WO | disclosed |
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045570-A1 | PHOSPHINE-LIGATED PALLADIUM SULFONATE PALLADACYCLES | PHOSPHO1, PDCD1, PDCD1LG2 | CA2 3754/4885SMN1; SMN2 680/4885HPGD 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.