Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890515 | 0.83 | MEN1 (0.42) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL27647920 | 0.81 | POLB (0.49) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL27647919 | 0.80 | ALOX5 (0.46) | ALOX5SMN1; SMN2ALDH1A1CYP1A2POLB | |
| SCHEMBL27745565 | 0.80 | KMT2A (0.42) | ALOX5CYP1A2POLBCYP2D6CYP2C9 | |
| SCHEMBL25222547 | 0.76 | ALOX5 (0.43) | ALOX5SMN1; SMN2ALDH1A1CYP1A2POLB | |
| SCHEMBL27828808 | 0.76 | ALOX5 (0.43) | ALOX5SMN1; SMN2ALDH1A1CYP1A2POLB | |
| SCHEMBL25222546 | 0.76 | ALOX5 (0.43) | ALOX5SMN1; SMN2ALDH1A1CYP1A2POLB | |
| SCHEMBL27805296 | 0.76 | LMNA (0.43) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4958199 | 0.74 | KMT2A (0.45) | ALOX5SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28485803 | 0.73 | CA12 (0.35) | MAPTCYP2D6CYP2C9LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761902-B | 6-phenanthridinone derivative and preparation method and application thereof | 四川大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-109761902-A | 6- phenanthridines ketone derivatives and its preparation method and application | 四川大学 | 2019-05-17 | — | — | CN | disclosed |