Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enbucrilate SCHEMBL24796 | 0.90 | TSHR (0.66) | TSHRALDH1A1HPGDATMTHRB | |
| SCHEMBL21292580 | 0.86 | ALDH1A1 (0.71) | TSHRALDH1A1CYP2C9KDM4EMEN1 | |
| Enbucrilate SCHEMBL7079940 | 0.85 | TSHR (0.59) | TSHRALDH1A1HPGDCYP2C9ATM | |
| Enbucrilate SCHEMBL6465405 | 0.85 | TSHR (0.61) | TSHRALDH1A1HPGDATMEPHX1 | |
| Ocrylate SCHEMBL19579379 | 0.85 | TSHR (0.61) | TSHRALDH1A1HPGDATMEPHX1 | |
| Enbucrilate SCHEMBL29026258 | 0.85 | TSHR (0.61) | TSHRALDH1A1HPGDATMEPHX1 | |
| SCHEMBL618797 | 0.85 | TSHR (0.63) | TSHRALDH1A1HPGDATMEPHX1 | |
| SCHEMBL4888255 | 0.84 | TSHR (0.58) | TSHRALDH1A1HPGDATMMAPT | |
| Enbucrilate SCHEMBL20395020 | 0.84 | TSHR (0.58) | TSHRALDH1A1HPGDATMTHRB | |
| SCHEMBL4892534 | 0.84 | TSHR (0.58) | TSHRALDH1A1HPGDATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461380-A | Stent for joining tissue layers at discrete points | ETHICON INC | 2019-11-15 | — | — | CN | disclosed |
| CN-110461285-A | Skin closure system and device for improved flexibility and stretchability of a flexible joint | ETHICON INC | 2019-11-15 | — | — | CN | disclosed |
| CN-109789038-A | method and device for skin closure | 伊西康公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-108348357-A | device for wound closure | 伊西康有限责任公司 | 2018-07-31 | — | — | CN | disclosed |