Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400738 | 0.77 | MEN1 (0.43) | NAPRTSIRT6ALOX15MEN1KMT2A | |
| SCHEMBL27963674 | 0.66 | TSHR (0.53) | NAPRTTSHRALOX15MEN1KMT2A | |
| SCHEMBL24283708 | 0.65 | ALDH1A1 (0.52) | MEN1KMT2AGABRA1GABRA2GABRB2 | |
| SCHEMBL21298734 | 0.65 | ALDH1A1 (0.52) | MEN1KMT2AGABRA1GABRA2GABRB2 | |
| SCHEMBL28291705 | 0.62 | — | — | |
| SCHEMBL17450551 | 0.62 | KDM4E (0.41) | ALOX15MEN1KMT2AL3MBTL1HCAR2 | |
| SCHEMBL8801184 | 0.61 | ALDH1A1 (0.39) | SIRT6ALOX15MEN1KMT2AL3MBTL1 | |
| SCHEMBL25395169 | 0.61 | HDAC8 (0.50) | P4HTMTSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL7996974 | 0.61 | KMT2A (0.38) | TSHRMEN1KMT2AL3MBTL1HCAR2 | |
| SCHEMBL17450552 | 0.61 | GPR35 (0.40) | ALOX15MEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761906-A | A kind of substituted imidazole formate ester derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-17 | — | — | CN | disclosed |