SCHEMBL7996974

SCHEMBL7996974

Cc1ncc(C(=O)O)n1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B10 Q99714 2/20 0.38
GFER P55789 1/20 0.38
HCAR2 Q8TDS4 3/20 0.36
KDM4E B2RXH2 5/20 0.36
MCL1 Q07820 2/20 0.36
GPR35 Q9HC97 1/20 0.36
GRN P28799 1/20 0.36
SORT1 Q99523 1/20 0.36
GSK3B P49841 1/20 0.36
DYRK1A Q13627 1/20 0.36
ALDH1A1 P00352 4/20 0.33
HPGD P15428 2/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16632983 0.84 ALOX15 (0.38) GSK3BDYRK1AALDH1A1SMN1; SMN2LMNA
SCHEMBL17450551 0.84 KDM4E (0.41) KMT2AMEN1L3MBTL1HSD17B10GFER
SCHEMBL17450552 0.78 GPR35 (0.40) KMT2AMEN1L3MBTL1HSD17B10GFER
SCHEMBL25457958 0.78 LMNA (0.35) KMT2AMEN1GSK3BDYRK1AALDH1A1
SCHEMBL10579577 0.78 SMN1; SMN2 (0.52) KMT2AMEN1L3MBTL1KDM4EGSK3B
SCHEMBL1046980 0.77 HRH3 (0.46) KMT2AMEN1HSD17B10ALDH1A1SMN1; SMN2
SCHEMBL3400738 0.77 MEN1 (0.43) KMT2AMEN1L3MBTL1HSD17B10GFER
SCHEMBL3496090 0.77 MCL1 (0.40) KMT2AMEN1L3MBTL1HSD17B10GFER
SCHEMBL13982981 0.77 L3MBTL1 (0.38) KMT2AMEN1L3MBTL1HSD17B10GFER
SCHEMBL19175805 0.77 CYP1A2 (0.44) KMT2AMEN1L3MBTL1HSD17B10GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167944-B Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-08-23 CN claimed
CN-114315728-A Imidazole ionic liquid and application thereof in alcoholysis polymerization of 2, 5-furandicarboxylic acid ester 中国科学院大连化学物理研究所 2022-04-12 CN claimed
EP-4007758-B1 BIS-[N-((5-CARBAMOYL)-1H-BENZO[D]IMIDAZOL-2-YL)-PYRAZOL-5-CARBOXAMIDE] DERIVATIVES AND RELATED COMPOUNDS AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS FOR THE TREATMENT OF CANCER MERSANA THERAPEUTICS INC (US) 2026-05-13 EP disclosed
US-20250011339-A1 STING AGONIST COMPOUNDS AND METHODS OF USE MERSANA THERAPEUTICS, INC. 2025-01-09 US disclosed
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-14 US disclosed
CN-110167944-B Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-08-23 CN disclosed
US-20240270715-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-08-15 US disclosed
EP-4192813-B1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-08-14 EP disclosed
US-11993729-B2 Chemical mechanical polishing composition BASF SE (DE) 2024-05-28 US disclosed
US-11939343-B2 Sting agonist compounds and methods of use MERSANA THERAPEUTICS, INC. (US) 2024-03-26 US disclosed
CN-117561241-A Inhibitors of transglutaminase 策迪拉有限公司 2024-02-13 CN disclosed
WO-2001055136-A1 BENZOXAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES SYNGENTA LIMITED (GB) 2001-08-02 WO disclosed
CN-1058490-C Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 2000-11-15 CN disclosed
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
CN-1122333-A Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 1996-05-15 CN disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed
EP-0306868-B1 PROCESS FOR THE PREPARATION OF 1-ALKYL IMIDAZOLES BASF Aktiengesellschaft (DE) 1991-12-27 EP disclosed
US-4864030-A Preparation of 1-alkylimidazoles BASF AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0306868-A1 Process for the preparation of 1-alkyl imidazoles BASF Aktiengesellschaft (DE) 1989-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11939343-B2 Sting agonist compounds and methods of use STING1, IRF3, MAVS KMT2A 3969/4885MEN1 4317/4885L3MBTL1 1155/4885
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 KMT2A 988/4885MEN1 590/4885L3MBTL1 3414/4885
US-20250011339-A1 STING AGONIST COMPOUNDS AND METHODS OF USE STING1, IRF3, MAVS KMT2A 3969/4885MEN1 4317/4885L3MBTL1 1155/4885
US-20240270715-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 KMT2A 988/4885MEN1 590/4885L3MBTL1 3414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.