Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28873710 | 0.98 | HSD17B10 (0.53) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15659227 | 0.75 | KDM4E (0.45) | NPC1ALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL13752162 | 0.75 | RAB9A (0.70) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14699551 | 0.75 | L3MBTL1 (0.57) | RAB9AALDH1A1TDP1HTTMAPT | |
| SCHEMBL6639975 | 0.75 | HSD17B10 (0.53) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4974907 | 0.74 | CDC7 (0.50) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28172564 | 0.73 | TLR8 (0.39) | HSD17B10RAB9ANPC1ALDH1A1TDP1 | |
| SCHEMBL10975367 | 0.73 | HSD17B10 (0.66) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10973574 | 0.73 | HSD17B10 (0.66) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7508433 | 0.72 | HSD17B10 (0.50) | HSD17B10RAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110327344-A | Quianzolinones are in preparation with tumour in relation to the application in terms of drug | 徐州医科大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-109748910-A | A kind of quianzolinones, preparation method and medical usage | 徐州医科大学 | 2019-05-14 | — | — | CN | disclosed |