SCHEMBL28299646

SCHEMBL28299646

O=CNc1cccc2c1C(C1CCCN1)CCC2

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.38
ADRA1A P35348 2/20 0.37
HSD11B1 P28845 1/20 0.36
PARP1 P09874 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8811949 0.94 ADRA1A (0.43) DRD2ADRA1AHSD11B1PARP1
SCHEMBL8811945 0.94 ADRA1A (0.43) DRD2ADRA1AHSD11B1PARP1
SCHEMBL8808448 0.86 ADRA1A (0.34) DRD2ADRA1AHSD11B1PARP1
SCHEMBL8808442 0.86 ADRA1A (0.34) DRD2ADRA1AHSD11B1PARP1
SCHEMBL16635504 0.74 HTR1A (0.45) DRD2PARP1
SCHEMBL16635902 0.69 DRD2 (0.54) DRD2ADRA1AHSD11B1
SCHEMBL9964020 0.69 DRD2 (0.61) DRD2ADRA1AHSD11B1
SCHEMBL15139403 0.69 DRD2 (0.61) DRD2ADRA1AHSD11B1
SCHEMBL1874596 0.69 ADRA1A (0.49) DRD2ADRA1AHSD11B1
SCHEMBL1875289 0.69 ADRA1A (0.49) DRD2ADRA1AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105636947-B N- heteroaryl (thio) carbonyl -2- (Benzocycloalkene -1- base) cyclammonium and its purposes as fungicide 拜耳作物科学股份公司 2019-05-07 CN disclosed