Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.91 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.35 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | INPP5B | P32019 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.35 |
| ▸ | ITPR3 | Q14573 | 3/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.33 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL9751415 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL8535679 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL2348555 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL10585386 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL2403605 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL514881 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL5141446 | 1.00 | FDPS (0.91) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL9799845 | 0.96 | FDPS (0.83) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL564839 | 0.96 | FDPS (0.83) | FDPSBLMTDP1CA4CA2 | |
| Pyrophosphoric Acid SCHEMBL565146 | 0.96 | FDPS (0.83) | FDPSBLMTDP1CA4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3261091-A | — | — | None | — | — | JP | disclosed |
| WO-2024105943-A1 | LITHIUM-ION CONDUCTIVE GLASS CERAMIC PRECURSOR | 株式会社オハラ | 2024-05-23 | — | — | WO | disclosed |
| EP-2786975-B1 | REFRACTORY PRODUCT AND CASTING NOZZLE | KROSAKIHARIMA CORP (JP) | 2019-01-02 | — | — | EP | disclosed |
| US-9221099-B2 | Refractory material and casting nozzle | KROSAKIHARIMA CORPORATION (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9072983-B2 | Vinyl sulfonic acid, polymer thereof, and production method thereof | ASAHI KASEI FINECHEM CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-2786975-A1 | REFRACTORY AND NOZZLE FOR CASTING | Krosakiharima Corporation (JP) | 2014-10-08 | — | — | EP | disclosed |
| US-20130334263-A1 | REFRACTORY MATERIAL AND CASTING NOZZLE | KROSAKIHARIMA CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20110017954-A1 | VINYL SULFONIC ACID, POLYMER THEREOF, AND PRODUCTION METHOD THEREOF | ASAHI KASEI FINECHEM CO., LTD. (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2269981-A1 | VINYLSULFONIC ACID, POLYMER OF THE SAME, AND METHOD FOR PRODUCING THE SAME | Asahi Kasei Finechem Co., Ltd. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-7497107-B2 | Gas sensing material and gas inspecting method | FUJI PHOTO FILM CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-20050207944-A1 | Gas sensing material and gas inspecting method | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| EP-1557669-A1 | Gas sensing material and gas inspecting method | FUJI PHOTO FILM CO., LTD. (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-6652823-B2 | Treatment of vanadium compound with formic acid, water and phosphorus compound | HALDOR TOPSOE A/S (DK) | 2003-11-25 | — | — | US | disclosed |
| US-20020115562-A1 | Process for the synthesis of VPO catalysts | HALDOR TOPSOE A/S | 2002-08-22 | — | — | US | disclosed |
| EP-1110603-A1 | Process for the synthesis of VPO catalysts | Haldor Topsoe A/S (DK) | 2001-06-27 | — | — | EP | disclosed |
| JP-H03261091-A | ELECTROLUMINESCENT ELEMENT | PIONEER ELECTRON CORP | 1991-11-20 | — | — | JP | disclosed |
| US-4983441-A | ACIDIC PHOSPHOROUS COMPOUND AND COPPER COMPOUND | NIPPON ZEON CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |