Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299754 | 0.86 | XDH (0.53) | XDHSIRT2SIRT1SIRT3 | |
| SCHEMBL28298333 | 0.86 | KMT2A (0.53) | RAB9AMEN1KMT2AXDHSIRT2 | |
| SCHEMBL28299731 | 0.84 | MEN1 (0.61) | MEN1ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL28298334 | 0.83 | GRM4 (0.64) | RAB9AXDH | |
| SCHEMBL28299759 | 0.82 | MEN1 (0.59) | MEN1ALDH1A1POLBKMT2AXDH | |
| SCHEMBL28299760 | 0.79 | ALDH1A1 (0.60) | RAB9AMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL28873490 | 0.78 | ALDH1A1 (0.59) | RAB9AMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL1649298 | 0.76 | LRRK2 (0.77) | SGMS2 | |
| SCHEMBL11548021 | 0.75 | NPC1 (0.68) | RAB9AMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL30464270 | 0.75 | XDH (0.64) | RAB9AMEN1ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |