Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299723 | 0.86 | RAB9A (0.65) | XDHSIRT2SIRT1SIRT3 | |
| SCHEMBL28298337 | 0.83 | ALDH1A1 (0.48) | — | |
| SCHEMBL28298335 | 0.82 | ALDH1A1 (0.53) | — | |
| SCHEMBL28298347 | 0.82 | XDH (0.52) | XDH | |
| SCHEMBL28298333 | 0.80 | KMT2A (0.53) | XDHSIRT2SIRT1SIRT3 | |
| SCHEMBL28298334 | 0.79 | GRM4 (0.64) | XDH | |
| SCHEMBL28299730 | 0.78 | — | — | |
| SCHEMBL28299766 | 0.75 | MRGPRX4 (0.47) | SIRT2SIRT1SIRT3 | |
| SCHEMBL28299752 | 0.74 | MEN1 (0.47) | XDH | |
| SCHEMBL29081318 | 0.72 | RAB9A (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |