Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471005 | 0.80 | L3MBTL1 (0.53) | TLR7HCRTR1DHODHHCRTR2SSTR1 | |
| SCHEMBL30368262 | 0.77 | KDM4E (0.50) | TLR7HCRTR1DHODHHCRTR2HSD17B13 | |
| SCHEMBL2301103 | 0.77 | KDM4E (0.50) | TLR7HCRTR1DHODHHCRTR2HSD17B13 | |
| SCHEMBL15142683 | 0.76 | SMN1; SMN2 (0.45) | TLR7HCRTR1HCRTR2HSD17B13ADORA2A | |
| SCHEMBL31307011 | 0.76 | BRD4 (0.53) | TLR7HCRTR1P2RY1 | |
| SCHEMBL28152819 | 0.75 | CASP3 (0.38) | GAA | |
| SCHEMBL16571480 | 0.70 | HCRTR1 (0.40) | TLR7HCRTR1DHODHHCRTR2HSD17B13 | |
| SCHEMBL28102316 | 0.69 | HCRTR1 (0.41) | HCRTR1HCRTR2GAA | |
| SCHEMBL13419577 | 0.68 | SLC40A1 (0.40) | DHODHRXRARXRBRXRGSLC40A1 | |
| SCHEMBL17506347 | 0.68 | TLR7 (0.40) | TLR7HCRTR1HSD17B13ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956929-A | Hete rocyclic derivatives, preparation method, pharmaceutical composition and application | 上海迪诺医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |