Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278650 | 0.78 | KDM4E (0.52) | KDM4ELMNAGAAMAPTPKM | |
| SCHEMBL28281957 | 0.76 | KDM4E (0.62) | POLBGUSBADORA2AADORA1KDM4E | |
| SCHEMBL28278673 | 0.76 | KDM4E (0.41) | ADORA2AADORA1KDM4ELMNAGAA | |
| SCHEMBL28281958 | 0.75 | CFTR (0.46) | ADORA2AADORA1KDM4ELMNAMAPT | |
| SCHEMBL28277279 | 0.72 | KDM4E (0.66) | POLBGUSBADORA2AKDM4ELMNA | |
| SCHEMBL28277278 | 0.72 | LMNA (0.49) | KDM4ELMNAGAAMAPTMEN1 | |
| SCHEMBL28280657 | 0.72 | ADORA2A (0.52) | POLBADORA2AADORA1KDM4ELMNA | |
| SCHEMBL5101956 | 0.70 | MAPT (0.44) | POLBKDM4ELMNAGAAMAPT | |
| SCHEMBL29956188 | 0.69 | ALDH1A1 (0.53) | KDM4ELMNAGAAMAPTHTT | |
| SCHEMBL3661878 | 0.69 | ALDH1A1 (0.53) | KDM4ELMNAGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796417-A | A series of structure of quinokysalines derivatives, Preparation method and use | 北京理工大学 | 2019-05-24 | — | — | CN | disclosed |