Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277279 | 0.84 | KDM4E (0.66) | ADORA2AALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL28815572 | 0.79 | ADORA2A (0.61) | ADORA2AALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL28278650 | 0.78 | KDM4E (0.52) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL28281958 | 0.78 | CFTR (0.46) | ADORA2AALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL7690919 | 0.77 | L3MBTL1 (0.61) | ADORA2AALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL30462969 | 0.72 | ADORA2A (0.53) | ADORA2AALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL3430716 | 0.72 | ADORA2A (0.50) | ADORA2AALDH1A1KDM4EL3MBTL1TDP1 | |
| SCHEMBL28299920 | 0.72 | POLB (0.48) | ADORA2AALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL20561472 | 0.71 | TOP1 (0.55) | ADORA2AALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL28280658 | 0.71 | ERBB2 (0.54) | ALDH1A1KDM4EL3MBTL1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422699-A | A kind of synthetic method of alpha-keto amide class compound | 浙江工业大学 | 2019-03-05 | — | — | CN | disclosed |