Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29487486 | 0.98 | CA12 (0.54) | CA12CA9CA1CA3CA4 | |
| SCHEMBL252706 | 0.98 | CA12 (0.54) | CA12CA9CA1CA3CA4 | |
| SCHEMBL3368797 | 0.83 | CA12 (0.60) | CA12CA9CA1CA3CA4 | |
| SCHEMBL25903990 | 0.77 | GAA (0.50) | CA12CA9CA1CA3CA4 | |
| SCHEMBL25904005 | 0.77 | CDK4 (0.50) | CA12CA9CA1CA3CA4 | |
| SCHEMBL4288324 | 0.77 | CA12 (0.52) | CA12CA9CA1CA3CA4 | |
| SCHEMBL31741308 | 0.75 | HRH4 (0.39) | CA12CA9CA1CA3CA4 | |
| SCHEMBL17951770 | 0.75 | MAPK1 (0.68) | CA12CA9CA1CA3CA4 | |
| SCHEMBL4290533 | 0.73 | CA12 (0.53) | CA12CA9CA1CA3CA4 | |
| SCHEMBL708122 | 0.72 | DAO (0.56) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098855-A | A kind of method for preparing the quinolinone of 7 hydroxyl 2 | 上海诺星医药科技有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-109776408-A | A kind of preparation method of 7- hydroxyl -2- quinolinone | 上海医药工业研究院 | 2019-05-21 | — | — | CN | disclosed |