SCHEMBL29487486

SCHEMBL29487486

O=c1ccc2ccc(O)cc2[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.54
CA9 Q16790 3/20 0.54
CA1 P00915 2/20 0.54
CA3 P07451 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA13 Q8N1Q1 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
GLA P06280 2/20 0.53
GAA P10253 2/20 0.53
HPGD P15428 2/20 0.53
TYR P14679 1/20 0.52
CA2 P00918 1/20 0.50
F11 P03951 1/20 0.47
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL252706 1.00 CA12 (0.54) CA12CA9CA1CA3CA4
SCHEMBL28299982 0.98 CA12 (0.52) CA12CA9CA1CA3CA4
SCHEMBL3368797 0.85 CA12 (0.60) CA12CA9CA1CA3CA4
SCHEMBL25903990 0.79 GAA (0.50) CA12CA9CA1CA3CA4
SCHEMBL25904005 0.79 CDK4 (0.50) CA12CA9CA1CA3CA4
SCHEMBL4288324 0.78 CA12 (0.52) CA12CA9CA1CA3CA4
SCHEMBL31741308 0.77 HRH4 (0.39) CA12CA9CA1CA3CA4
SCHEMBL17951770 0.77 MAPK1 (0.68) CA12CA9CA1CA3CA4
SCHEMBL4290533 0.75 CA12 (0.53) CA12CA9CA1CA3CA4
SCHEMBL708122 0.74 DAO (0.56) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119470715-A Method for determining impurity compound I and impurity compound II in key material of bripiprazole 宁波大红鹰药业股份有限公司 2025-02-18 CN claimed
CN-118580229-B Preparation method of bripiprazole 湖南一格制药有限公司 2024-12-27 CN claimed
CN-118580229-A Preparation method of bripiprazole 湖南一格制药有限公司 2024-09-03 CN claimed
CN-114181202-A Preparation method of brexpiprazole 湖南省湘中制药有限公司 2022-03-15 CN claimed
CN-121735928-A Brexperiment Process for preparing azoles 浙江工业大学 2026-03-27 CN disclosed
CN-121081468-A Application of 7-hydroxy-2 (1H) -quinolinone difluoro ethyl acetate-containing derivative in preparation of anti-triple negative breast cancer drugs 遵义医科大学 2025-12-09 CN disclosed
CN-121059606-A Antitumor application of 7-hydroxy-2 (1H) -quinolinone trifluoromethyl-containing derivative 遵义医科大学 2025-12-05 CN disclosed
CN-121059606-A Antitumor application of 7-hydroxy-2 (1H) -quinolinone trifluoromethyl-containing derivative 遵义医科大学 2025-12-05 CN disclosed
CN-119462586-B Coumarin derivative and application thereof 安徽中医药大学 2025-05-06 CN disclosed
CN-119462500-A Preparation method of 7- (4-chlorobutoxy) -1H-quinolin-2-one 湖南省湘中制药有限公司 2025-02-18 CN disclosed
CN-119462586-A Coumarin derivative and application thereof 安徽中医药大学 2025-02-18 CN disclosed
CN-119470715-A Method for determining impurity compound I and impurity compound II in key material of bripiprazole 宁波大红鹰药业股份有限公司 2025-02-18 CN disclosed
CN-117986244-A Quinolinone derivative and preparation method and application thereof 江苏恩华药业股份有限公司 2024-05-07 CN disclosed
CN-117769545-A Tri-fused ring derivative-containing regulator, preparation method and application thereof 上海枢境生物科技有限公司 2024-03-26 CN disclosed
CN-117384129-A Impurity compound, preparation method and application thereof 浙江九洲药业股份有限公司 2024-01-12 CN disclosed
CN-114835709-B Azaergoline derivative, and preparation method and application thereof 上海科技大学 2023-10-20 CN disclosed
CN-115521298-A Preparation method of brexpiprazole 江苏慧聚药业股份有限公司 2022-12-27 CN disclosed
CN-115279756-A METTL3 modulators 埃克森特治疗公司 2022-11-01 CN disclosed
CN-114835709-A Aza-ergoline derivative and preparation method and application thereof 上海科技大学 2022-08-02 CN disclosed
CN-114181202-A Preparation method of brexpiprazole 湖南省湘中制药有限公司 2022-03-15 CN disclosed