Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25903990 | 0.89 | GAA (0.50) | CDK4CCND1GAAKDM4EALDH1A1 | |
| SCHEMBL3368797 | 0.81 | CA12 (0.60) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL29487486 | 0.79 | CA12 (0.54) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL252706 | 0.79 | CA12 (0.54) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL28299982 | 0.77 | CA12 (0.52) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL30171457 | 0.76 | CA12 (0.61) | CDK4CCND1GAAKDM4EALDH1A1 | |
| SCHEMBL3847120 | 0.76 | CA12 (0.61) | CDK4CCND1GAAKDM4EALDH1A1 | |
| SCHEMBL25903858 | 0.75 | KDM4E (0.58) | GAAKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11097088 | 0.74 | GAA (0.73) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL5316444 | 0.74 | CA12 (0.59) | CDK4CCND1GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |