Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28300209 | 0.80 | RAF1 (0.45) | RAF1GAAALDH1A1HPGDGFER | |
| SCHEMBL28300148 | 0.78 | RAF1 (0.42) | RAF1GAAALDH1A1HPGDGFER | |
| SCHEMBL28873510 | 0.77 | RAB9A (0.55) | RAF1GAAALDH1A1HPGDGFER | |
| SCHEMBL28298682 | 0.74 | ALDH1A1 (0.56) | GAAALDH1A1HPGDGFERRAB9A | |
| SCHEMBL28298714 | 0.73 | RAF1 (0.41) | RAF1GAAALDH1A1HPGDGFER | |
| SCHEMBL28196751 | 0.73 | RAF1 (0.46) | RAF1GAAALDH1A1RAB9ADAO | |
| SCHEMBL28300152 | 0.72 | RAB9A (0.41) | RAF1GAAALDH1A1HPGDGFER | |
| SCHEMBL28300136 | 0.71 | RAB9A (0.40) | RAF1GAAALDH1A1HPGDGFER | |
| SCHEMBL8031103 | 0.70 | TSHR (0.44) | RAF1GAAALDH1A1HPGDRAB9A | |
| SCHEMBL28873511 | 0.69 | RAF1 (0.41) | RAF1GAAALDH1A1GFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963858-A | N3The thieno uracil and application thereof that ring-type replaces | 拜耳股份公司 | 2019-07-02 | — | — | CN | disclosed |