Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28067715 | 0.88 | MAPT (0.43) | IDO1MAPK1MAPTPKMSMN1; SMN2 | |
| SCHEMBL27229142 | 0.80 | TSHR (0.58) | MAPK1MAPTSMN1; SMN2ALDH1A1PDE7A | |
| SCHEMBL28301221 | 0.79 | MAPT (0.39) | IDO1MAPK1MAPTPKMALDH1A1 | |
| SCHEMBL27229152 | 0.78 | MAPT (0.49) | MAPK1MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11483675 | 0.76 | MAPT (0.54) | MAPK1MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL10784739 | 0.76 | GPR35 (0.51) | MAPK1MAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL28322481 | 0.74 | TDP1 (0.58) | MAPK1MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL28067659 | 0.74 | MAPT (0.43) | IDO1MAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18815092 | 0.73 | TSHR (0.54) | MAPTPKMSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3953683 | 0.73 | ALDH1A1 (0.51) | MAPK1MAPTSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |