Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229152 | 0.81 | MAPT (0.49) | TSHRMAPK1TDP1ALDH1A1HPGD | |
| SCHEMBL29812157 | 0.81 | PDE7A (0.61) | TSHRMAPK1PDE7ATDP1ALDH1A1 | |
| SCHEMBL9539494 | 0.81 | PDE7A (0.61) | TSHRMAPK1PDE7ATDP1ALDH1A1 | |
| SCHEMBL11483675 | 0.80 | MAPT (0.54) | TSHRMAPK1PDE7ATDP1ALDH1A1 | |
| SCHEMBL10784739 | 0.80 | GPR35 (0.51) | TSHRMAPK1TDP1ALDH1A1HPGD | |
| SCHEMBL28301045 | 0.80 | IDO1 (0.42) | TSHRMAPK1PDE7ATDP1ALDH1A1 | |
| SCHEMBL18815092 | 0.77 | TSHR (0.54) | TSHRPDE7ATDP1ALDH1A1LMNA | |
| SCHEMBL3953683 | 0.77 | ALDH1A1 (0.51) | TSHRMAPK1ALDH1A1HPGDCA1 | |
| SCHEMBL11257078 | 0.76 | LMNA (0.49) | TSHRMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL2777612 | 0.75 | PDE7A (0.55) | TSHRMAPK1PDE7ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573094-A2 | CDK2 INHIBITORS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20240174665-A1 | CDK2 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024039903-A2 | CDK2 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174665-A1 | CDK2 INHIBITORS AND USES THEREOF | CDK2, CDK20, CDK1 | TSHR 4345/4885MAPK1 1037/4885PDE7A 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.