Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395333 | 0.76 | KDM4E (0.56) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL9670397 | 0.74 | KDM4E (0.57) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL16792476 | 0.74 | KDM4E (0.51) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL19523362 | 0.73 | KDM4E (0.50) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL5953265 | 0.72 | KDM4E (0.55) | SMN1; SMN2KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL22113999 | 0.72 | KDM4E (0.54) | SMN1; SMN2KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL30497266 | 0.71 | HPGD (0.62) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL4784069 | 0.70 | CYP2C19 (0.60) | SMN1; SMN2KDM4EPOLBLMNATSPO | |
| SCHEMBL22075813 | 0.70 | NPC1 (0.44) | SMN1; SMN2KDM4EALDH1A1NPC1POLB | |
| SCHEMBL22113991 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |