Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16792476 | 0.88 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL19523362 | 0.87 | KDM4E (0.50) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL24187368 | 0.83 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4297543 | 0.83 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28961226 | 0.82 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30396830 | 0.82 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7970314 | 0.81 | ALDH1A1 (0.58) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20893365 | 0.80 | RAB9A (0.57) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL23012695 | 0.75 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4292449 | 0.75 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |