SCHEMBL28301249

SCHEMBL28301249

O=C(Nc1ccc(-c2cc(-c3ccccc3)[nH]n2)cc1)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.72
ACHE P22303 1/20 0.72
RAB9A P51151 3/20 0.64
NPC1 O15118 2/20 0.64
BCAT2 O15382 1/20 0.61
POLB P06746 1/20 0.59
PTPN1 P18031 4/20 0.58
PTPN2 P17706 1/20 0.57
MAPT P10636 1/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ROCK2 O75116 1/20 0.54
ROCK1 Q13464 1/20 0.54
ACR P10323 2/20 0.52
DEGS1 O15121 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1789941 0.86 RAB9A (0.63) BCHEACHERAB9ANPC1POLB
SCHEMBL22307326 0.85 KMT2A (0.62) BCHEACHERAB9ANPC1POLB
SCHEMBL25437962 0.85 KMT2A (0.62) BCHEACHERAB9ANPC1POLB
SCHEMBL27823165 0.85 RAB9A (0.61) BCHEACHERAB9ANPC1POLB
SCHEMBL22415393 0.81 BCHE (0.54) BCHEACHERAB9ANPC1BCAT2
SCHEMBL29033877 0.81 BCHE (0.65) BCHEACHERAB9ANPC1POLB
SCHEMBL1528761 0.81 BCHE (0.56) BCHEACHERAB9ANPC1POLB
SCHEMBL23784328 0.81 BCHE (0.51) BCHEACHERAB9ANPC1BCAT2
SCHEMBL1528382 0.80 BCHE (0.55) BCHEACHERAB9ANPC1POLB
SCHEMBL27716724 0.80 ACR (0.70) POLBMAPTACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761844-B Method for preparing 1- (4-benzoylamino-phenyl) -3-phenylpropane-1, 3-diketone by one-pot method 常州南京大学高新技术研究院 2021-11-09 CN disclosed
CN-109761844-A A kind of method that one kettle way prepares 1- (4- benzamido-phenyl) -3- phenyl-propane -1,3- diketone 常州南京大学高新技术研究院 2019-05-17 CN disclosed