Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ACR | P10323 | 2/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764249 | 0.86 | ACR (0.69) | MAPTACRKMT2AMEN1 | |
| SCHEMBL29033879 | 0.84 | MEN1 (0.57) | BCHEACHENPC1RAB9AMAPT | |
| SCHEMBL20764122 | 0.84 | NPC1 (0.52) | BCHEACHENPC1RAB9AMAPT | |
| SCHEMBL9048096 | 0.83 | KMT2A (0.64) | NPC1RAB9AMAPTKMT2AMEN1 | |
| Bromide SCHEMBL31659833 | 0.82 | KMT2A (0.62) | NPC1RAB9AMAPTKMT2AMEN1 | |
| Bromide SCHEMBL26095595 | 0.82 | KMT2A (0.62) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL28301249 | 0.81 | BCHE (0.72) | BCHEACHENPC1RAB9AMAPT | |
| SCHEMBL25308935 | 0.81 | MAPT (0.67) | BCHEACHENPC1RAB9AMAPT | |
| SCHEMBL20764247 | 0.79 | ACR (0.74) | MAPTACR | |
| SCHEMBL2409003 | 0.79 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394934-B | Pyrazole benzamide compound as well as preparation method and application thereof | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |