Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921417 | 0.79 | MAOA (0.60) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL28188822 | 0.79 | MAOA (0.60) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL7828455 | 0.79 | MAOA (0.60) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL7831602 | 0.79 | MAOA (0.56) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL5306849 | 0.79 | MAOA (0.76) | MAOAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL11540656 | 0.77 | MAOA (0.57) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL2897463 | 0.76 | GPR35 (0.68) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL2904975 | 0.76 | MAOA (0.56) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL31634119 | 0.76 | MAOA (0.56) | MAOAALDH1A1PDE10ATDP1GPR35 | |
| SCHEMBL10565737 | 0.75 | MAOA (0.55) | MAOAALDH1A1PDE10ATDP1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867645-A | A kind of synthetic method of 2,2- bis- fluoro- 2,3- dihydro substitution benzofuran compounds | 中国医学科学院药物研究所 | 2019-06-11 | — | — | CN | disclosed |