Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777597 | 0.80 | GPR35 (0.60) | MAOAALDH1A1ERN1MAPTGPR35 | |
| SCHEMBL15340799 | 0.77 | MAOA (0.54) | MAOAALDH1A1PDE10AERN1MAPT | |
| SCHEMBL7828455 | 0.77 | MAOA (0.60) | MAOAALDH1A1PDE10AMAPTGPR35 | |
| SCHEMBL28301342 | 0.77 | MAOA (0.60) | MAOAALDH1A1PDE10AMAPTGPR35 | |
| SCHEMBL28188822 | 0.77 | MAOA (0.60) | MAOAALDH1A1PDE10AMAPTGPR35 | |
| SCHEMBL27921417 | 0.77 | MAOA (0.60) | MAOAALDH1A1PDE10AMAPTGPR35 | |
| SCHEMBL3085553 | 0.74 | MAPT (0.62) | MAOACYP2A6ALDH1A1ERN1MAPT | |
| SCHEMBL28088702 | 0.74 | MAOA (0.50) | MAOAALDH1A1PDE10AERN1MAPT | |
| SCHEMBL2897463 | 0.73 | GPR35 (0.68) | MAOAALDH1A1PDE10AMAPTGPR35 | |
| SCHEMBL31634119 | 0.73 | MAOA (0.56) | MAOAALDH1A1PDE10AMAPTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266986-A1 | Cytotoxins, Prodrugs, Linkers and Stabilizers useful therefor | Medarex, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| US-4159274-A | 7-Nitro-2-benzofurancarboximidamide hydrochloride | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-06-26 | — | — | US | disclosed |