Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830185 | 1.00 | ADORA2A (0.33) | ADORA2AADORA1DYRK1A | |
| SCHEMBL5841377 | 0.80 | ALDH1A1 (0.32) | ADORA2AADORA1DYRK1A | |
| SCHEMBL29752139 | 0.79 | NPC1 (0.36) | DYRK1A | |
| SCHEMBL4306636 | 0.78 | DYRK1A (0.31) | ADORA2AADORA1DYRK1A | |
| SCHEMBL27952254 | 0.75 | NCF1 (0.39) | ADORA2AADORA1DYRK1A | |
| SCHEMBL10865972 | 0.75 | ADORA2A (0.30) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6853662 | 0.74 | NCF1 (0.38) | ADORA2AADORA1DYRK1A | |
| SCHEMBL30917959 | 0.74 | NCF1 (0.38) | ADORA2AADORA1DYRK1A | |
| SCHEMBL8080125 | 0.72 | ADORA2A (0.35) | ADORA2AADORA1DYRK1A | |
| SCHEMBL8944768 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| EP-1874790-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH Aachen (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108678-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2006-10-19 | — | — | WO | disclosed |
| EP-1712557-A1 | New s-adenosyl-L-methionine analogues with extended activated groups for transfer by methyltransferases | RWTH Aachen (DE) | 2006-10-18 | — | — | EP | disclosed |