Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 8/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827078 | 0.91 | PPARG (0.55) | CMKLR1CXCR4ELANEPPARGPPARA | |
| SCHEMBL13170504 | 0.75 | CMKLR1 (0.58) | CMKLR1CXCR4ELANEPPARGPPARA | |
| SCHEMBL13170502 | 0.72 | CMKLR1 (0.59) | CMKLR1CXCR4ELANEPPARGPPARA | |
| SCHEMBL6544018 | 0.72 | PPARA (0.78) | CMKLR1CXCR4PPARGPPARAPPARD | |
| SCHEMBL6544258 | 0.71 | PPARA (0.83) | CMKLR1CXCR4PPARGPPARAPPARD | |
| SCHEMBL6543891 | 0.70 | PPARA (0.84) | CMKLR1CXCR4PPARGPPARAPPARD | |
| SCHEMBL6543456 | 0.70 | PPARA (0.84) | CMKLR1CXCR4PPARGPPARAPPARD | |
| SCHEMBL6543468 | 0.70 | PPARA (0.84) | CMKLR1CXCR4PPARGPPARAPPARD | |
| SCHEMBL2828315 | 0.70 | ATP4A (0.47) | PLA2G2A | |
| SCHEMBL5679022 | 0.69 | ELANE (0.58) | CMKLR1CXCR4ELANEPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931659-B1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS (FR) | 2010-09-08 | — | — | EP | disclosed |
| EP-1931659-B1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS (FR) | 2010-09-08 | — | — | EP | disclosed |
| US-7655679-B2 | Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions | SANOFI-AVENTIS (FR) | 2010-02-02 | — | — | US | disclosed |
| US-7655679-B2 | Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions | SANOFI-AVENTIS (FR) | 2010-02-02 | — | — | US | disclosed |
| US-7655679-B2 | Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions | SANOFI-AVENTIS (FR) | 2010-02-02 | — | — | US | disclosed |
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | US | disclosed |
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | US | disclosed |
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | US | disclosed |
| EP-1931659-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007039176-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039176-A1 | DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227834-A1 | DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | PPARA, PPARD, PPARG | CMKLR1 2730/4885CXCR4 2259/4885ELANE 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.