Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368498 | 0.69 | GLA (0.38) | HTR1ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL19990602 | 0.69 | GLA (0.38) | HTR1ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL30733533 | 0.68 | MAOB (0.47) | HTR1ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL20936679 | 0.68 | MAOB (0.47) | HTR1ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL994856 | 0.68 | MAOB (0.47) | HTR1ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL28524004 | 0.67 | ALDH1A1 (0.43) | EPHX2 | |
| SCHEMBL3411535 | 0.67 | KMT2A (0.47) | EPHX2 | |
| Hydrochloric Acid SCHEMBL994709 | 0.67 | MAOB (0.46) | HTR1ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL4480785 | 0.66 | EPHX2 (0.49) | EPHX2 | |
| SCHEMBL3662286 | 0.65 | DPP8 (0.45) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843894-A | Beta-lactamase inhibitor | 诺华股份有限公司 | 2019-06-04 | — | — | CN | disclosed |