SCHEMBL20936679

SCHEMBL20936679

c1ccc(CON[C@@H]2CCCNC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.47
KDM1A O60341 2/20 0.47
CHRNB2 P17787 2/20 0.41
CHRNA4 P43681 2/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR1A P08908 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
EED O75530 1/20 0.38
F10 P00742 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
MAOA P21397 2/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994856 1.00 MAOB (0.47) MAOBKDM1ACHRNB2CHRNA4CHRM2
SCHEMBL30733533 1.00 MAOB (0.47) MAOBKDM1ACHRNB2CHRNA4CHRM2
Hydrochloric Acid SCHEMBL994709 0.98 MAOB (0.46) MAOBKDM1ACHRNB2CHRNA4CHRM2
Oxalic Acid SCHEMBL28136322 0.83 KMT2A (0.38) MAOBKDM1AF10MEN1ALDH1A1
SCHEMBL28524004 0.82 ALDH1A1 (0.43) MEN1ALDH1A1KMT2A
SCHEMBL3411535 0.82 KMT2A (0.47) MEN1ALDH1A1KMT2A
SCHEMBL4480785 0.80 EPHX2 (0.49) MEN1ALDH1A1KMT2A
SCHEMBL19872325 0.78 KDM1A (0.32) MAOBKDM1ACHRNB2CHRNA4CHRM2
SCHEMBL22710505 0.77 ALDH1A1 (0.53) MEN1ALDH1A1KMT2AHTR2C
SCHEMBL994345 0.76 SLC6A2 (0.52) MAOBKDM1ASLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707784-A Process for preparing amino acid derivatives 株式会社API 2025-03-28 CN disclosed
CN-112930338-B Process for preparing amino acid derivatives 株式会社API 2024-12-24 CN disclosed
US-12103928-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2024-10-01 US disclosed
CN-117447285-A Preparation method of chiral impurity of beta-lactamase inhibitor intermediate 赤峰迪生药业有限责任公司 2024-01-26 CN disclosed
CN-117447285-A Preparation method of chiral impurity of beta-lactamase inhibitor intermediate 赤峰迪生药业有限责任公司 2024-01-26 CN disclosed
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-10-19 US disclosed
CN-116772561-A But reuse's dehydrating agent drying equipment for medicine preparation 常州红太阳药业有限公司 2023-09-19 CN disclosed
US-11731971-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-08-22 US disclosed
CN-115707686-A Method for refining avibactam sodium initial raw material 四川科伦药物研究院有限公司 2023-02-21 CN disclosed
US-11142499-B1 Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof XINFA PHARMACEUTICAL CO., LTD (CN) 2021-10-12 US disclosed
WO-2019075990-A1 SIMPLE PREPARATION METHOD FOR AVIBACTAM INTERMEDIATE 新发药业有限公司 2019-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731971-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 MAOB 258/4885KDM1A 790/4885CHRNB2 1025/4885
US-11142499-B1 Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof GLUL, GRIN2D, GRIN2C MAOB 2278/4885KDM1A 2158/4885CHRNB2 1672/4885
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 MAOB 258/4885KDM1A 790/4885CHRNB2 1025/4885
US-12103928-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 MAOB 258/4885KDM1A 790/4885CHRNB2 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.