Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARS1 | P26639 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27196595 | 0.92 | TARS1 (0.33) | TARS1ADORA2ADOT1LADORA3ADORA2B | |
| SCHEMBL31326251 | 0.90 | TARS1 (0.36) | TARS1ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL28494144 | 0.90 | TARS1 (0.36) | TARS1ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL31406475 | 0.89 | ADORA2A (0.36) | TARS1ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL31192374 | 0.85 | ADORA2A (0.35) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL28120771 | 0.85 | TARS1 (0.35) | TARS1 | |
| SCHEMBL29435121 | 0.81 | TARS1 (0.38) | TARS1ADORA1 | |
| SCHEMBL16987222 | 0.81 | TARS1 (0.38) | TARS1ADORA1 | |
| SCHEMBL28564130 | 0.81 | TARS1 (0.38) | TARS1ADORA1 | |
| SCHEMBL29089525 | 0.80 | TARS1 (0.39) | TARS1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843915-A | Genetically engineered cell and preparation method thereof | 朱诺治疗学股份有限公司 | 2019-06-04 | — | — | CN | disclosed |