SCHEMBL28494144

SCHEMBL28494144

CC(O)C(N)C(=O)Nc1ncnc2c1ncn2[C@]1(C(N)=O)O[C@H](CO)[C@@H](O)C1(O)O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TARS1 P26639 2/20 0.36
▸ ADORA2A P29274 2/20 0.35
▸ ADORA3 P0DMS8 2/20 0.35
▸ ADORA2B P29275 1/20 0.35
▸ ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31326251 1.00 TARS1 (0.36) TARS1ADORA2AADORA3ADORA2BADORA1
SCHEMBL31192374 0.95 ADORA2A (0.35) ADORA2AADORA3ADORA2BADORA1
SCHEMBL31406475 0.92 ADORA2A (0.36) TARS1ADORA2AADORA3ADORA2BADORA1
SCHEMBL28304158 0.90 TARS1 (0.34) TARS1ADORA2AADORA3ADORA2BADORA1
SCHEMBL27196595 0.89 TARS1 (0.33) TARS1ADORA2AADORA3ADORA2BADORA1
SCHEMBL28120771 0.88 TARS1 (0.35) TARS1
SCHEMBL16987222 0.83 TARS1 (0.38) TARS1ADORA1
SCHEMBL28564130 0.83 TARS1 (0.38) TARS1ADORA1
SCHEMBL29435121 0.83 TARS1 (0.38) TARS1ADORA1
SCHEMBL29089525 0.82 TARS1 (0.39) TARS1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 — — CN disclosed
CN-120129532-A Stabilized lipid or lipid nanoparticle suspensions 埃泽瑞斯公司 2025-06-10 — — CN disclosed
CN-119895037-A System for enhancing target mRNA expression and uses thereof 约翰霍普金斯大学 2025-04-25 — — CN disclosed
CN-113423418-B Treatment of cilia disease 埃泽瑞斯公司 2025-01-10 — — CN disclosed
CN-118949075-A Treatment of cilia disease 埃泽瑞斯公司 2024-11-15 — — CN disclosed
CN-117729930-A Use of IFN-lambda mRNA for the treatment of viral infections 埃泽瑞斯公司 2024-03-19 — — CN disclosed
CN-116887812-A Formulations for aerosol formation and aerosols for delivery of nucleic acids 埃泽瑞斯公司 2023-10-13 — — CN disclosed
CN-113423418-A Treatment of cilia disease 埃泽瑞斯公司 2021-09-21 — — CN disclosed
CN-113396219-A Purification of mRNA by tangential flow filtration 埃泽瑞斯公司 2021-09-14 — — CN disclosed
CN-113286597-A Precisely engineered invisible messenger RNAs and other polynucleotides 科纳勒生物公司 2021-08-20 — — CN disclosed
CN-112004942-A Analysis and diagnosis method using RNA modification 国立大学法人大阪大学 2020-11-27 — — CN disclosed
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