SCHEMBL16987222

SCHEMBL16987222

C[C@@H](O)[C@H](N)C(=O)Nc1ncnc2c1ncn2[C@]1(C(N)=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TARS1 P26639 2/20 0.38
▸ SLC29A1 Q99808 1/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435121 1.00 TARS1 (0.38) TARS1SLC29A1ADORA1LMNATP53
SCHEMBL28564130 1.00 TARS1 (0.38) TARS1SLC29A1ADORA1LMNATP53
SCHEMBL29089525 0.88 TARS1 (0.39) TARS1SLC29A1ADORA1
SCHEMBL28475028 0.87 SLC29A1 (0.46) SLC29A1ADORA1LMNATP53ALOX15
SCHEMBL26090156 0.86 HTR2B (0.35) TARS1ADORA1
SCHEMBL29413061 0.86 HTR2B (0.35) TARS1ADORA1
SCHEMBL28300819 0.85 ADORA3 (0.35) TARS1ADORA1
SCHEMBL30950292 0.85 TARS1 (0.37) TARS1SLC29A1ADORA1
SCHEMBL31675871 0.84 AHCY (0.41) ADORA1
SCHEMBL17627818 0.84 RXFP1 (0.39) SLC29A1ADORA1LMNATP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768532-A Method for producing nucleic acid 辉瑞公司 2025-04-04 — — CN disclosed
WO-2025054355-A1 METHODS, SYSTEMS, AND COMPOSITIONS FOR EXOGENOUS CONTROL OF PROTEIN EXPRESSION RADAR THERAPEUTICS INC. (US) 2025-03-13 — — WO disclosed
CN-118201625-A9 Microalgae extracellular vesicles, preparation and use thereof AGS治疗简易股份公司 2024-10-01 — — CN disclosed
CN-118201625-A Microalgae extracellular vesicles, preparation and use thereof AGS治疗简易股份公司 2024-06-14 — — CN disclosed
US-11884937-B2 Activation of innate immunity for enhanced nuclear reprogramming of somatic cells with mRNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-01-30 — — US disclosed
CN-116113696-A Gene editing to improve joint function 奥泽生物疗法公司 2023-05-12 — — CN disclosed
US-20230045590-A1 GENETICALLY CORRECTED CELLS FOR THERAPEUTIC USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-02-09 — — US disclosed
EP-3991751-A1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH MRNA The Board of Trustees of the Leland Stanford Junior University (US) 2022-05-04 — — EP disclosed
EP-3104889-B1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH MRNA UNIV LELAND STANFORD JUNIOR (US) 2021-10-13 — — EP disclosed
WO-2021133724-A1 GENETICALLY CORRECTED CELLS FOR THERAPEUTIC USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2021-07-01 — — WO disclosed
US-20210130792-A1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-05-06 — — US disclosed
US-10760061-B2 Activation of innate immunity for enhanced nuclear reprogramming of somatic cells with mRNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-09-01 — — US disclosed
US-9738873-B2 Activation of innate immunity for enhanced nuclear reprogramming of somatic cells with mRNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2017-08-22 — — US disclosed
US-20170204376-A1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2017-07-20 — — US disclosed
EP-3104889-A1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA The Board Of Trustees Of The Leland Stanford Junior University (US) 2016-12-21 — — EP disclosed
US-20150225699-A1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-08-13 — — US disclosed
WO-2015120225-A1 ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2015-08-13 — — WO disclosed
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