Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARS1 | P26639 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494144 | 0.88 | TARS1 (0.36) | TARS1 | |
| SCHEMBL31326251 | 0.88 | TARS1 (0.36) | TARS1 | |
| SCHEMBL31406475 | 0.87 | ADORA2A (0.36) | TARS1 | |
| SCHEMBL28304158 | 0.85 | TARS1 (0.34) | TARS1 | |
| SCHEMBL27196595 | 0.83 | TARS1 (0.33) | TARS1 | |
| SCHEMBL31192374 | 0.83 | ADORA2A (0.35) | — | |
| SCHEMBL28564130 | 0.80 | TARS1 (0.38) | TARS1 | |
| SCHEMBL29435121 | 0.80 | TARS1 (0.38) | TARS1 | |
| SCHEMBL16987222 | 0.80 | TARS1 (0.38) | TARS1 | |
| SCHEMBL27918607 | 0.79 | ADORA3 (0.31) | TARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110430894-A | Immunomodulatory therapeutic MRNA compositions encoding peptides that activate oncogene mutations | MODERNATX INC | 2019-11-08 | — | — | CN | disclosed |
| CN-110402145-A | For enhancing the messenger RNA and its application method of immune response | MODERNATX INC | 2019-11-01 | — | — | CN | disclosed |
| CN-110036107-A | TCR α homing endonuclease variants | 蓝鸟生物公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109689865-A | BCL11A HOMING ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE | 蓝鸟生物公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109312340-A | CRISPR-CPF1 correlation technique, composition and component for immunotherapy for cancer | 爱迪塔斯医药公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109153994-A | CRISPR/CAS related methods and compositions for treating β -hemoglobinopathies | 爱迪塔斯医药公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108779462-A | Composition for treating hemoglobinopathy and method | 诺华股份有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-108138183-A | For CRISPR-CAS correlation techniques, composition and the component of immunotherapy for cancer | 爱迪塔斯医药公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108026526-A | CRISPR/CAS related methods and compositions for improved transplantation | 爱迪塔斯医药公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-106459995-A | CRISPR-associated methods and compositions using dominant grnas | 爱迪塔斯医药有限公司 | 2017-02-22 | — | — | CN | disclosed |